Title

Stereocontrolled intramolecular ketone-olefin reductive coupling reactions promoted by samarium diiodide

Document Type

Article

Publication Date

1987

Publication Title

Tetrahedron Letters

Abstract

The stereocontrolled intramolecular coupling of unsaturated β-ketoesters and β-ketoamides is reported. Good yields of highly substituted β-hydroxycyclopentanecarboxylates are generated in the process, with substantial and predictable stereochemical control at three contiguous stereocenters.

Excellent stereochemical control is achieved over three stereocenters in the ittle reaction.

Comments

Published as Caryn Kenny.

Copyright © 1987 Published by Elsevier Ltd.

Share

COinS