Stereocontrolled intramolecular ketone-olefin reductive coupling reactions promoted by samarium diiodide
Document Type
Article
Publication Date
1987
Publication Title
Tetrahedron Letters
Abstract
The stereocontrolled intramolecular coupling of unsaturated β-ketoesters and β-ketoamides is reported. Good yields of highly substituted β-hydroxycyclopentanecarboxylates are generated in the process, with substantial and predictable stereochemical control at three contiguous stereocenters.
Excellent stereochemical control is achieved over three stereocenters in the ittle reaction.
Recommended Citation
Molander, G.A., & Kenny, C. (1987). Stereocontrolled intramolecular ketone-olefin reductive coupling reactions promoted by samarium diiodide. Tetrahedron Letters. 28(38), 4367-4370. doi.org/10.1016/S0040-4039(00)96511-0
COinS
Comments
Published as Caryn Kenny.
Copyright © 1987 Published by Elsevier Ltd.