Date of Award

5-13-2015

Document Type

Open Access Thesis

Degree Name

Master of Science (MS)

Department

Applied Medical Science

First Advisor

Stephen C. Pelsue

Second Advisor

Samuel M. Duboise

Third Advisor

Ah-Kau Ng

Keywords

Autoimmune disorders, Hepatitis C, viruses

Abstract

The plasma membrane protein Efr3b, the Tetratricopeptide domain repeat 7 (Ttc7), and the kinase phosphatidylinositol 4-kinase III alpha (PI4KIIIa) are found to form a complex a the plasma membrane. This complex is thought to play a role regulating the PI4P pools at the plasma membrane, which is imperative to membrane identity and vesicle transport.

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