Effects of 5-Aza-2' Deoxycitidine and Sulforaphane on Major Histocompatibility Complex (MHC) classes I and II surface expression in human acute T-cell leukemia cell Jurkat

Author

Ali Salam Abdullah MS, University of Southern Maine

Date of Award

10-2014

Call Number

QR184.315 .A23 2014

Document Type

Open Access Thesis

Degree Name

Master of Science (MS)

Department

Applied Medical Science

First Advisor

Ah-Kau Ng

Second Advisor

Stephen Pelsue

Third Advisor

Ronald Rubocki

Keywords

Applied medical science, Deoxycitidine, Sulforaphane, T-cell leukemia

Abstract

The immune system cells recognize and kill cancer cells by engaging the tumor antigens on the surfaces of cancer cells presented by the Major Histocompatibility Complex (MHC). Cancer cells can escape from immune system cells recognition and/or killing by down-regulating the MHC expression through genetic or epigenetic mechanisms.

Recommended Citation

Abdullah, Ali Salam MS, "Effects of 5-Aza-2' Deoxycitidine and Sulforaphane on Major Histocompatibility Complex (MHC) classes I and II surface expression in human acute T-cell leukemia cell Jurkat" (2014). All Student Scholarship. 69.
https://digitalcommons.usm.maine.edu/etd/69